The danger model: questioning an unconvincing theory
نویسندگان
چکیده
منابع مشابه
Network Proactive Defense Model Based on Immune Danger Theory
Recent investigations into proactive network defense have not produced a systematic methodology and structure; in addition, issues including multi-source information fusion and attacking behavior analysis have not been resolved. Borrowing ideas of danger sensing and immune response from danger theory, a proactive network defense model based on danger theory is proposed. This paper defines the s...
متن کاملExercise does not protect the female heart: an unconvincing conclusion?
An Unconvincing Conclusion? To the Editor: The recent article by Paroo et al1 addressed an important issue relating to the sex difference in exercise-induced late cardioprotection against ischemia-reperfusion (I-R) injury. This study prompts a few concerns that I would like to share with the Editors and the readers of Circulation Research. (1) Exercise-induced cardioprotection in females. In th...
متن کاملSTLR: a novel danger theory based structural TLR algorithm
Artificial Immune Systems (AIS) have long been used in the field of computer security and especially in Intrusion Detection systems. Intrusion detection based on AISs falls into two main categories. The first generation of AIS is inspired from adaptive immune reactions but, the second one which is called danger theory focuses on both adaptive and innate reactions to build a more biologically-re...
متن کاملTumors and the danger model.
This article reviews the evidence for the danger model in the context of immune response to tumors and the insufficiency of the immune system to eliminate tumor growth. Despite their potential immunogenicity tumors do not induce significant immune responses which could destroy malignant cells. According to the danger model, the immune surveillance system fails to detect tumor antigens because t...
متن کاملThe danger theory: 20 years later
The self-non-self theory has dominated immunology since the 1950s. In the 1990s, Matzinger and her colleagues suggested a new, competing theory, called the "danger theory." This theory has provoked mixed acclaim: enthusiasm and criticism. Here we assess the danger theory vis-à-vis recent experimental data on innate immunity, transplantation, cancers and tolerance to foreign entities, and try to...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Immunology & Cell Biology
سال: 2016
ISSN: 0818-9641,1440-1711
DOI: 10.1038/icb.2016.29